TAK-653 Osavampator 1358751-06-0 Purity: ≥98.0% (HPLC) Hot Sale
Ruifu Chemical is the leading manufacturer of TAK-653 (Osavampator) (CAS: 1358751-06-0) with high quality.
Purchase TAK-653 (Osavampator) (CAS: 1358751-06-0), please contact us by e-mail: alvin@ruifuchem.com
| Chemical Name | TAK-653 |
| Synonyms | Osavampator; NBI-1065845; Pyrazino[2,1-c][1,2,4]thiadiazine, 9-[4-(cyclohexyloxy)phenyl]-3,4-dihydro-7-methyl-, 2,2-dioxide; 9-(4-(Cyclohexyloxy)phenyl)-7-methyl-3,4-dihydropyrazino[2,1-c][1,2,4]thiadiazine 2,2-dioxide |
| Stock Status | In Stock |
| CAS Number | 1358751-06-0 |
| Molecular Formula | C19H23N3O3S |
| Molecular Weight | 373.47 g/mol |
| EINECS | 1592732-453-0 |
| Boiling Point | 540.8±52.0℃(lit.) (Predicted) |
| Solubility | DMSO 10 mg/mL |
| Density | 1.38±0.1 g/cm3 (Predicted) |
| Storage Temperature | Store at 2-8℃, Protected From Moisture and Light, and Kepp Dry, Sealed |
| Shipping | Ambient |
| COA & MSDS | Available |
| Origin of Product | Shanghai, China |
| Stability | Stable for at Least 2 Years After Receipt When Stored Properly |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | Yellow Solid | Yellow Solid |
| Purity / Analysis Method | ≥98.0% (HPLC) | 99.06% |
| 1 HNMR | Conforms to Structure | Conforms |
| Conclusion | The product has been tested and complies with the given specifications | |
(1) Certificate of Analysis (COA)
(2) Material Safety Data Sheet (MSDS) available along with product
(3) For more information, please contact with our product manager by e-mail: alvin@ruifuchem.com
Package:Bottle, 1kg/bag, 5kg/bag, or according to customer's requirement.
Storage Condition:Sealed storage, away from moisture and light. Store in a cool, dry (2-8℃) and well-ventilated warehouse away.
Shipping:Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience?We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal.
1358751-06-0 - Application:
Osavampator (TAK-653) is a AMPA receptor positive allosteric modulator. Osavampator selectively binds to AMPA-R in a glutamate-dependent manner and induces Ca2+ influx in hGluA1i CHO cells (EC50 = 3.3 μM). Osavampator improves learning and memory in many models. Osavampator is can be used for the research of depressive disorders.
TAK-653 is a selective positive allosteric modulator (PAM) of AMPA receptors exhibiting minimal agonistic activity, elicits an antidepressant-like response while maintaining a favorable safety profile in rat models.




